Pregnancy Tests: Diagnostic pregnancy assessments depending on immunological reactions among HCG and anti-HCG may perhaps cause false-adverse or Phony-optimistic interpretations.
Disposal of Unused Promethazine HCl and Codeine Phosphate Oral Resolution Recommend patients to correctly get rid of unused Promethazine HCl and Codeine Phosphate Oral Remedy. Recommend patients to throw the drug within the domestic trash following these techniques. 1) Clear away them from their initial containers and blend them having an unwanted compound, such as employed coffee grounds or kitty litter (this makes the drug a lot less captivating to children and pets, and unrecognizable to individuals who may perhaps intentionally go in the trash trying to find medications).
Respiratory difficulties (respiratory despair)that may result in Demise and opioid withdrawal can take place if You begin getting or stop getting other medicines though getting Promethazine Hydrochloride and Codeine Phosphate Oral Solution, together with:
Antihistamines are contraindicated to be used inside the treatment of lower respiratory tract signs and symptoms, such as asthma.
Prevention and control of nausea and vomiting related to selected kinds of anesthesia and surgery.
There's no common settlement about certain pharmacological cure regimens for uncomplicated NMS.
Lower Seizure Threshold - Promethazine may possibly reduced seizure threshold. It should be website made use of with warning in folks with seizure Diseases or in persons who are working with concomitant medications, including narcotics or nearby anesthetics, which can also have an affect on seizure threshold.
Long-expression animal studies have not been carried out to evaluate the carcinogenic potential of Promethazine, nor are there other animal or human details regarding carcinogenicity, mutagenicity, or impairment of fertility using this type of drug. Promethazine was nonmutagenic while in the Salmonella exam process of Ames.
sedation, reduction of nervousness, and creation of gentle sleep from which the affected person may be easily aroused
Outcomes within the Cardiovascular Process Codeine makes peripheral vasodilation which may result in orthostatic hypotension or syncope. Manifestations of histamine launch and/or peripheral vasodilation may perhaps involve pruritus, flushing, purple eyes and sweating and/or orthostatic hypotension.
Extreme drowsiness and diminished mental alertness. Promethazine HCl Oral Solution may induce drowsiness which can impair your power to journey a bike, drive a car or truck, or run equipment.
The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric individuals a lot less than six years of age, mainly because The mixture may possibly lead to lethal respiratory melancholy During this age inhabitants (see WARNINGS Box Warning and Use in Pediatric Sufferers).
Respiratory depression bringing about arrest, coma, and Dying has happened with using codeine antitussives in youthful little ones, significantly in the beneath-one-12 months infants whose capability to deactivate the drug just isn't absolutely designed.
Promethazine Indicators and symptoms of overdosage with promethazine range from gentle despair of your central anxious technique and cardiovascular technique to profound hypotension, respiratory melancholy, unconsciousness and sudden Dying.